Fusilev

Fusilev is a brand name of levoleucovorin calcium, approved by the FDA in the following formulation(s):

FUSILEV (levoleucovorin calcium - powder; iv (infusion))

• 
  Manufacturer: SPECTRUM PHARMS
  
  Approval date: March 7, 2008
  
  Strength(s): EQ 50MG BASE/VIAL ^[RLD]

FUSILEV (levoleucovorin calcium - solution; iv (infusion))

• 
  Manufacturer: SPECTRUM PHARMS
  
  Approval date: April 29, 2011
  
  Strength(s): EQ 175MG BASE/17.5ML (EQ 10MG BASE/ML) ^[RLD], EQ 250MG BASE/25ML (EQ 10MG BASE/ML) ^[RLD]

Has a generic version of Fusilev been approved?

No. There is currently no therapeutically equivalent version of Fusilev available.

Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Fusilev. These medications may be counterfeit and potentially unsafe. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. Ask your health care provider for advice if you are unsure about the online purchase of any medication.

See also: About generic drugs.

Related Patents

Patents are granted by the U.S. Patent and Trademark Office at any time during a drug's development and may include a wide range of claims.

• 
  Substantially pure diastereoisomers of tetrahydrofolate derivatives
  Patent 6,500,829
  Issued: December 31, 2002
  Inventor(s): Hamish Christopher Swan; Wood & Colin James; Suckling & Lilias G.; Rees
  Assignee(s): University of Strathclyde
  The present invention related to the preparation of substantially pure diastereoisomers of derivatives of tetrahydrofolate and the use of such diastereoisomers. More particularly the present invention provides a process for the preparation of a desired substantially pure (6R or 6S) diastereoisomer of a derivative of tetrahydrofolic acid or salt or ester. The process comprises the steps of: attaching a chiral auxiliary group at either N-5 or N-10 of a mixture of 6R and 6S diastereoisomers of tetrahydrofolic acid, separating the new diastereoisomers, recovering the desired new diastereoisomer (6R or 6S) corresponding to the desired (6R or 6S) diastereoisomer, and converting the substantially pure new diastereoisomer recovered into the corresponding diastereoisomer.
  
  Patent expiration dates:
  
  
  • December 31, 2019
    
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    Drug substance
    ✓ 
    Drug product
  
  

Related Exclusivities

Exclusivity is exclusive marketing rights granted by the FDA upon approval of a drug and can run concurrently with a patent or not. Exclusivity is a statutory provision and is granted to an NDA applicant if statutory requirements are met.

• Exclusivity expiration dates:
  • March 7, 2011 - NEW PRODUCT
  
  
  • April 29, 2014 - USE IN COMBINATION CHEMOTHERAPY WITH 5-FLUOROURACIL IN THE PALLIATIVE TREATMENT OF PATIENTS WITH ADVANCED METASTATIC COLORECTAL CANCER
  
  
  • March 7, 2015 - ORPHAN DRUG EXCLUSIVITY
  
  
  • April 29, 2018 - ORPHAN DRUG EXCLUSIVITY
  
  

See also...

• Fusilev Consumer Information (Wolters Kluwer)
• Fusilev Consumer Information (Cerner Multum)
• Fusilev Advanced Consumer Information (Micromedex)
• Fusilev AHFS DI Monographs (ASHP)
• Levoleucovorin Consumer Information (Drugs.com)
• Levoleucovorin Calcium Consumer Information (Wolters Kluwer)
• Levoleucovorin 1 Consumer Information (Cerner Multum)
• Levoleucovorin Consumer Information (Cerner Multum)
• Levoleucovorin Intravenous Advanced Consumer Information (Micromedex)
• Levoleucovorin Calcium AHFS DI Monographs (ASHP)

Propranolol HCl PCH

Propranolol HCl PCH may be available in the countries listed below.

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Propranolol

Propranolol hydrochloride (a derivative of Propranolol) is reported as an ingredient of Propranolol HCl PCH in the following countries:

• Netherlands

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Rimaped

Rimaped may be available in the countries listed below.

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Rifampicin

Rifampicin is reported as an ingredient of Rimaped in the following countries:

• Philippines

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Nystat

Nystat may be available in the countries listed below.

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Nystatin

Nystatin is reported as an ingredient of Nystat in the following countries:

• Bangladesh

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Nimesulide Jet

Nimesulide Jet may be available in the countries listed below.

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Nimesulide

Nimesulide is reported as an ingredient of Nimesulide Jet in the following countries:

• Italy

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Carlatrend

Carlatrend may be available in the countries listed below.

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Carvedilol

Carvedilol is reported as an ingredient of Carlatrend in the following countries:

• Taiwan

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Nubend

Nubend may be available in the countries listed below.

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Albendazole

Albendazole is reported as an ingredient of Nubend in the following countries:

• Sri Lanka

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Nebivolol-Actavis

Nebivolol-Actavis may be available in the countries listed below.

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Nebivolol

Nebivolol hydrochloride (a derivative of Nebivolol) is reported as an ingredient of Nebivolol-Actavis in the following countries:

• Austria


• Germany

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Bendamen

Bendamen may be available in the countries listed below.

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Mebendazole

Mebendazole is reported as an ingredient of Bendamen in the following countries:

• Venezuela

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Dotropina

Dotropina may be available in the countries listed below.

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Dobutamine

Dobutamine is reported as an ingredient of Dotropina in the following countries:

• Peru

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Nicotinamide

Scheme

Rec.INN

ATC (Anatomical Therapeutic Chemical Classification)

A11HA01

CAS registry number (Chemical Abstracts Service)

0000098-92-0

Chemical Formula

C6-H6-N2-O

Molecular Weight

122

Therapeutic Category

Vitamin B-complex

Chemical Name

3-Pyridinecarboxamide

Foreign Names

• Nicotinamidum (Latin)
• Nicotinamid (German)
• Nicotinamide (French)
• Nicotinamida (Spanish)

Generic Names

• Nicotinamide (OS: DCF, DCIT, JAN)
• Antipellagra-Vitamin (IS)
• Nicamid (IS)
• Nicosedine (IS)
• Nicotinic acid amide (IS)
• Nicotylamidum (IS)
• Pyridin-3-carboxamid (IS)
• Vitamin B₃ (IS)
• Vitamine PP (IS)
• Niacinamide (PH: USP 32)
• Nicotinamid (PH: Ph. Eur. 6)
• Nicotinamide (PH: Ph. Eur. 6, Ph. Int. 4, JP XIV, BP 2010)
• Nicotinamidum (PH: Ph. Int. 4, Ph. Eur. 6)

Brand Names

• NB-3
  Sigma, Argentina



• Niacef
  Surya Dermato Medica, Indonesia



• Niacex Isdin
  Isdin, Chile



• Niacex-S Isdin
  Isdin, Chile



• Niacinamida
  Natural Life, Argentina



• Nicam
  Dermal, United Kingdom; Dermal, Ireland



• Nicobion
  Merck, Germany; Teofarma, France



• Nicotinamid
  Zonnebode Seiyaku, Japan



• Nicotinamide IDI
  IDI, Italy



• Nicotinamide Ratiopharm
  ratiopharm, Netherlands



• Nicotinsäureamid Jenapharm
  Mibe Jena, Germany



• Stomin A (Nicotinamide and Papaverine)
  Zonnebode Seiyaku, Japan



• Ucemine PP
  Pierre Fabre, Belgium; UCB, Luxembourg



• Vitamina PP Angelini
  Angelini, Italy



• Vitaminum PP
  GlaxoSmithKline, Poland; Polfa Kutno, Poland; Polfarmex, Poland

International Drug Name Search

Glossary

DCF	Dénomination Commune Française
DCIT	Denominazione Comune Italiana
IS	Inofficial Synonym
JAN	Japanese Accepted Name
OS	Official Synonym
PH	Pharmacopoeia Name
Rec.INN	Recommended International Nonproprietary Name (World Health Organization)

Click for further information on drug naming conventions and International Nonproprietary Names.

Baci-IM injection

Generic Name: bacitracin (injection) (BAS i TRAY sin)

Brand Names: Baci-IM

What is bacitracin?

Bacitracin injection is an antibiotic that treats staph infection caused by a bacteria called staphylococcus (STAF-il-oh-KOK-us).

Bacitracin injection is used in infants to treat pneumonia. It is also used to treat an infection that causes pus to build up between the lungs and the membrane that covers them.

Bacitracin injection may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Baci-IM (bacitracin (injection))?

Before your child receives bacitracin injection, tell the doctor if the child has a history of kidney disease.

Many other drugs can damage the kidneys and should not be used together with bacitracin. Tell your doctor if your child is receiving chemotherapy, medicines used to treat a bowel disorder, medications to prevent organ transplant rejection, antiviral medications, or any other injected antibiotics.

Get emergency medical help if your child has any of these signs of an allergic reaction: hives; difficulty breathing; swelling of the face, lips, tongue, or throat.

Serious side effects of bacitracin injection include urinating less than usual or not at all, blood in the urine, lower back pain, or painful urination.

Make sure your child receives this medication for the entire length of time prescribed by the doctor. Your child's symptoms may get better before the infection is completely treated. Bacitracin injection will not treat a viral infection such as the common cold or flu.

What should I discuss with my health care provider before receiving Baci-IM (bacitracin (injection))?

Your child should not receive this medication if he or she is allergic to bacitracin.

Before receiving bacitracin injection, tell your child's doctor if the child is allergic to any drugs, or if your child has a history of kidney disease. If your child has either of these conditions, he or she may not be able to receive bacitracin, or may need dosage adjustments or special tests during treatment.

How is bacitracin injection given?

This medication is given as an injection into a muscle. A doctor, nurse, or other healthcare provider will give your child this injection.

Lung infections in infants are serious conditions, and your child will most likely be kept in the hospital while being treated with bacitracin injection.

To be sure this medication is not causing harmful effects, your child's kidney function may need to be tested on a regular basis. Do not miss any scheduled visits to your doctor.

Make sure your child receives this medication for the entire length of time prescribed by the doctor. Your child's symptoms may get better before the infection is completely treated. Bacitracin injection will not treat a viral infection such as the common cold or flu.

What happens if I miss a dose?

Since bacitracin injection is usually given in a hospital, it is not likely your child will miss a dose.

What happens if I overdose?

Tell your child's caregivers right away if you think the child has received too much of this medicine.

What should I avoid while receiving Baci-IM (bacitracin (injection))?

Follow your doctor's instructions about any restrictions on food, beverages, or activity while your child is receiving bacitracin injection.

Baci-IM (bacitracin (injection)) side effects

Get emergency medical help if your child has any of these signs of an allergic reaction: hives; difficulty breathing; swelling of the face, lips, tongue, or throat. While receiving bacitracin injection, your child will be watched for the following serious side effects:

• 
  

  urinating more than usual or more often;

  
  


• 
  

  urinating less than usual, or not at all (fewer wet diapers);

  
  


• 
  

  blood in the urine;

  
  


• 
  

  lower back pain; or

  
  


• 
  

  painful urination.

  
  

Less serious side effects include:

• 
  

  nausea, vomiting;

  
  


• 
  

  mild skin rash; or

  
  


• 
  

  pain, burning, or swelling where the medicine was injected.

  
  

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Baci-IM (bacitracin (injection))?

Before your child receives bacitracin, tell the doctor if your child is receiving any of the following drugs:

• 
  

  cancer medications (chemotherapy);

  
  


• 
  

  medicines used to treat a bowel disorder, such as mesalamine (Pentasa) or sulfasalazine (Azulfidine);

  
  


• 
  

  medicines used to prevent organ transplant rejection, such as sirolimus (Rapamune) or tacrolimus (Prograf);

  
  


• 
  

  any other injected antibiotics such as amikacin (Amikin), amphotericin B (Fungizone, AmBisome, Amphotec, Abelcet), or streptomycin; or

  
  


• 
  

  antiviral medicines such as adefovir (Hepsera), cidofovir (Vistide), or foscarnet (Foscavir).

  
  

Many of these other drugs can damage the kidneys. If your child is receiving any of these drugs, he or she may not be able to receive bacitracin, or may need dosage adjustments or special tests during treatment.

There may be other drugs that can affect bacitracin injection. Tell your doctor about all your child's prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your child's doctor.

More Baci-IM resources

• Baci-IM Side Effects (in more detail)
• Baci-IM Drug Interactions
• Baci-IM Support Group
• 0 Reviews for Baci-IM - Add your own review/rating

Compare Baci-IM with other medications

• Pneumonia

Where can I get more information?

• Your pharmacist can provide more information about bacitracin injection.

See also: Baci-IM side effects (in more detail)

Vetkelfizina

Vetkelfizina may be available in the countries listed below.

In some countries, this medicine may only be approved for veterinary use.

Ingredient matches for Vetkelfizina

Sulfamethoxypyridazine

Sulfamethoxypyridazine is reported as an ingredient of Vetkelfizina in the following countries:

• Italy

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Idroxicarbamide

Idroxicarbamide may be available in the countries listed below.

Ingredient matches for Idroxicarbamide

Hydroxycarbamide

Idroxicarbamide (DCIT) is also known as Hydroxycarbamide (Rec.INN)

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Glossary

DCIT	Denominazione Comune Italiana
Rec.INN	Recommended International Nonproprietary Name (World Health Organization)

Click for further information on drug naming conventions and International Nonproprietary Names.