Monday, 30 April 2012

Vi-Atro


Generic Name: atropine and diphenoxylate (A troe peen and DYE fen OX i late)

Brand Names: Lomotil, Lonox, Vi-Atro


What is Vi-Atro (atropine and diphenoxylate)?

Atropine affects the body in many different ways, such as reducing spasms in the bladder, stomach, and intestines.


Diphenoxylate is an antidiarrheal medication.


The combination of atropine and diphenoxylate is used to treat diarrhea.


Atropine and diphenoxylate may also be used for other purposes not listed in this medication guide.


What is the most important information I should know about Vi-Atro (atropine and diphenoxylate)?


If you are giving this medication to a child, pay close attention to the dose. An atropine and diphenoxylate overdose is more likely to occur in a child, and can cause breathing problems or result in death or permanent brain damage.

Use only the liquid form of this medicine in a child younger than 13 years old. Do not give atropine and diphenoxylate tablets to a child under 13.


Drink extra water while you are taking this medication to keep from getting dehydrated. It may take up to 48 hours of using this medicine before your symptoms improve. For best results, keep using the medication as directed. Talk with your doctor if your symptoms do not improve after 10 days of treatment.

What should I discuss with my healthcare provider before taking Vi-Atro (atropine and diphenoxylate)?


Do not use this medication if you are allergic to atropine or diphenoxylate, or if you have:

  • jaundice (yellowing of your skin or eyes caused by a liver disorder);




  • diarrhea that is caused by bacteria; or




  • diarrhea caused by taking an antibiotic.



Before taking atropine and diphenoxylate, tell your doctor if you are allergic to any drugs, or if you have:



  • blocked intestines;




  • an intestinal disorder such as ulcerative colitis or Crohn's disease;



  • liver disease;

  • kidney disease;


  • heart disease, heart rhythm problems, or high blood pressure;




  • glaucoma;




  • Down's syndrome;




  • a thyroid disorder;




  • problems with urination;




  • an enlarged prostate;




  • asthma or other lung problems; or




  • if you are dehydrated;



If you have any of these conditions, you may need a dose adjustment or special tests to safely take atropine and diphenoxylate.


FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Atropine and diphenoxylate may pass into breast milk and could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not give this medication to a child younger than 2 years old.

How should I take Vi-Atro (atropine and diphenoxylate)?


Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.


If you are giving this medication to a child, pay close attention to the dose. An atropine and diphenoxylate overdose is more likely to occur in a child, and can cause breathing problems or result in death or permanent brain damage.

Use only the liquid form of this medicine in a child younger than 13 years old. Do not give atropine and diphenoxylate tablets to a child under 13.


Take the medicine with a full glass of water. Drink extra water while you are taking atropine and diphenoxylate to keep from getting dehydrated. It may take up to 48 hours of using the medicine before your symptoms improve. For best results, keep using the medication as directed. Talk with your doctor if your symptoms do not improve after 10 days of treatment.

Measure liquid medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.


Store atropine and diphenoxylate at room temperature away from moisture and heat. Keep the medication where a child cannot reach it. An overdose of atropine and diphenoxylate can be fatal to a child.

What happens if I miss a dose?


Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention if you think you have used too much of this medicine, or if a child has accidentally swallowed it. An overdose of atropine and diphenoxylate can cause breathing problems and may result in death or permanent brain damage.

Early overdose symptoms may include dry skin, dry mouth or nose, blurred vision, restless feeling, feeling too warm or cold, tingly feeling, and a fast heart rate.


Progressing symptoms of an atropine and diphenoxylate overdose include weakness, pinpoint pupils in the eyes, weak or shallow breathing, fainting, or coma. Report any early overdose symptoms to your doctor as soon as possible.


What should I avoid while taking Vi-Atro (atropine and diphenoxylate)?


This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol while you are taking this medication. Alcohol can increase some of the side effects of atropine and diphenoxylate.

Cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety can add to sleepiness caused by atropine and diphenoxylate. Tell your doctor if you regularly use any of these other medicines.


Avoid becoming overheated or dehydrated during exercise and in hot weather. Follow your doctor's instructions about the type and amount of liquids you should drink.


Vi-Atro (atropine and diphenoxylate) side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have any of these serious side effects:

  • stomach pain or bloating;




  • ongoing or worsening diarrhea;




  • diarrhea that is watery or bloody;




  • numbness in your hands or feet;




  • depressed mood;




  • confusion, unusual thoughts or behavior;




  • fast heart rate; or




  • urinating less than usual or not at all.



Less serious side effects may include:



  • drowsiness, dizziness, headache;




  • tired or restless feeling;




  • nausea, vomiting, upset stomach, loss of appetite; or




  • skin rash, or itching.



This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect Vi-Atro (atropine and diphenoxylate)?


Before taking atropine and diphenoxylate, tell your doctor if you are using any of the following drugs:



  • a barbiturate such as amobarbital (Amytal), butabarbital (Butisol), mephobarbital (Mebaral), secobarbital (Seconal), or phenobarbital (Luminal, Solfoton); or




  • an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate).



This list is not complete and there may be other drugs that can interact with atropine and diphenoxylate. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.



More Vi-Atro resources


  • Vi-Atro Side Effects (in more detail)
  • Vi-Atro Use in Pregnancy & Breastfeeding
  • Vi-Atro Drug Interactions
  • Vi-Atro Support Group
  • 0 Reviews for Vi-Atro - Add your own review/rating


  • Vi-Atro Advanced Consumer (Micromedex) - Includes Dosage Information

  • Lomotil MedFacts Consumer Leaflet (Wolters Kluwer)

  • Lomotil Prescribing Information (FDA)



Compare Vi-Atro with other medications


  • Diarrhea


Where can I get more information?


  • Your pharmacist can provide more information about atropine and diphenoxylate.

See also: Vi-Atro side effects (in more detail)


Ichthomed




Ichthomed may be available in the countries listed below.


Ingredient matches for Ichthomed



Ichthammol

Ichthammol sodium salt, decolorized (a derivative of Ichthammol) is reported as an ingredient of Ichthomed in the following countries:


  • Germany

International Drug Name Search

Astepro Spray



Pronunciation: a-ZEL-as-teen
Generic Name: Azelastine
Brand Name: Astelin


Astepro Spray is used for:

Treating allergy symptoms such as sneezing and itchy, runny nose. It is also used to treat symptoms of nasal passage inflammation such as runny nose, stuffy nose, and postnasal drip. It may also be used for other conditions as determined by your doctor.


Astepro Spray is an antihistamine nasal spray. It works by blocking the action of histamine, which reduces allergy symptoms.


Do NOT use Astepro Spray if:


  • you are allergic to any ingredient in Astepro Spray

Contact your doctor or health care provider right away if any of these apply to you.



Before using Astepro Spray:


Some medical conditions may interact with Astepro Spray. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

Some MEDICINES MAY INTERACT with Astepro Spray. Because little, if any, of Astepro Spray is absorbed into the blood, the risk of it interacting with another medicine is low.


Ask your health care provider if Astepro Spray may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Astepro Spray:


Use Astepro Spray as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • An extra patient leaflet is available with Astepro Spray. Talk to your pharmacist if you have questions about this information.

  • Astepro Spray is for the nose only. Do not get it in your eyes or mouth. If you get Astepro Spray in your eyes, rinse with cool tap water at once.

  • Prime the spray pump before the first use of a new bottle. Remove the blue dust cover over the tip of the bottle and the blue safety clip. To prime the pump, point the spray pump away from you and others. Spray rapidly and firmly several times until a fine mist appears (4 sprays or less).

  • Gently blow your nose to clear your nostrils.

  • Keep your head tilted downward. Place the spray tip ¼ to ½ inch into the nostril. Hold the bottle upright, allowing the spray tip to aim toward the back of the nose. Close the other nostril with one finger.

  • Spray rapidly and firmly once and sniff gently at the same time. Repeat in the other nostril as directed.

  • Breathe in gently. Do not tilt your head back after using Astepro Spray. This will help you to avoid the bitter taste that may be caused by Astepro Spray.

  • After using Astepro Spray, wipe the spray tip with a clean tissue or cloth. Keep the dust cover and safety clip on the bottle when it is not in use.

  • If 3 or more days have passed since the last use of this bottle, reprime the pump with 2 sprays or until a fine mist appears.

  • If the nozzle becomes clogged, do NOT clean it by using a pointed object. Remove the spray pump from the bottle. Soak it in warm water, squirting it several times while under water. Dry the spray pump completely. Attach the spray pump to the bottle and reprime.

  • If you miss a dose of Astepro Spray, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Astepro Spray.



Important safety information:


  • Astepro Spray may cause drowsiness. These effects may be worse if you take it with alcohol or certain medicines. Use Astepro Spray with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

  • Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Astepro Spray; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.

  • Do NOT take more than the recommended dose without checking with your doctor.

  • The medicine has an antihistamine in it. Before you start any new medicine, check the label to see if it has an antihistamine (eg, diphenhydramine) in it too. If it does or if you are not sure, check with your doctor or pharmacist.

  • Astepro Spray may cause harm if it is swallowed. If you may have taken it by mouth, contact your poison control center or emergency room right away.

  • Astepro Spray should be used with extreme caution in CHILDREN younger than 5 years old; safety and effectiveness in these children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Astepro Spray while you are pregnant. It is not known if Astepro Spray is found in breast milk. If you are or will be breast-feeding while you use Astepro Spray, check with your doctor. Discuss any possible risks to your baby.


Possible side effects of Astepro Spray:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Bitter taste; drowsiness; fatigue; headache; mild nasal bleeding, burning, discomfort, or stinging; sudden sneezing attack.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); repeated or persistent nosebleeds; severe nasal irritation.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Astepro side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include increased limp muscles; saliva production; seizures; tremors.


Proper storage of Astepro Spray:

Store Astepro Spray at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Protect from freezing. Store with the pump tightly closed. Store away from heat, moisture, and light. Do not use Astepro Spray after the expiration date on the bottle. Keep Astepro Spray out of the reach of children and away from pets.


General information:


  • If you have any questions about Astepro Spray, please talk with your doctor, pharmacist, or other health care provider.

  • Astepro Spray is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Astepro Spray. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Astepro resources


  • Astepro Side Effects (in more detail)
  • Astepro Use in Pregnancy & Breastfeeding
  • Astepro Drug Interactions
  • Astepro Support Group
  • 14 Reviews for Astepro - Add your own review/rating


Compare Astepro with other medications


  • Hay Fever

Friday, 20 April 2012

Fluarix injectable


Generic Name: influenza virus vaccine (injectable) (in floo ENZ a VYE rus VAK seen)

Brand Names: Afluria, Fluarix, FluLaval, Fluvirin, Fluvirin Preservative-Free, Fluzone, Fluzone Preservative-Free, Fluzone Preservative-Free Pediatric


What is influenza virus injectable vaccine?

Influenza virus (commonly known as "the flu") is a serious disease caused by a virus. Influenza virus can spread from one person to another through small droplets of saliva that are expelled into the air when an infected person coughs or sneezes. The virus can also be passed through contact with objects the infected person has touched, such as a door handle or other surfaces.


Influenza virus vaccine is used to prevent infection caused by influenza virus. The vaccine is redeveloped each year to contain specific strains of inactivated (killed) flu virus that are recommended by public health officials for that year.


The injectable influenza virus vaccine (flu shot) is a "killed virus" vaccine. Influenza virus vaccine is also available in a nasal spray form, which is a "live virus" vaccine.

Influenza virus vaccine works by exposing you to a small dose of the virus, which helps your body to develop immunity to the disease. Influenza virus vaccine will not treat an active infection that has already developed in the body.


Influenza virus vaccine is for use in adults and children who are at least 6 months old.

Becoming infected with influenza (commonly known as "the flu") is much more dangerous to your health than receiving the vaccine to protect against it. Influenza causes thousands of deaths each year, and hundreds of thousands of hospitalizations. Like any medicine, this vaccine can cause side effects, but the risk of serious side effects is extremely low.


Like any vaccine, influenza virus vaccine may not provide protection from disease in every person. This vaccine will not prevent illness caused by avian flu ("bird flu").


What is the most important information I should know about this vaccine?


The injectable influenza virus vaccine (flu shot) is a "killed virus" vaccine. Influenza virus vaccine is also available in a nasal spray form, which is a "live virus" vaccine. This medication guide addresses only the injectable form of this vaccine.

You can still receive a vaccine if you have a cold or fever. In the case of a more severe illness with a fever or any type of infection, wait until you get better before receiving this vaccine.


Keep track of any and all side effects you have after receiving this vaccine. If you ever have to receive another influenza virus vaccine in the future, you will need to tell the doctor if the first shot caused any side effects.

Like any vaccine, influenza virus vaccine may not provide protection from disease in every person. This vaccine will not prevent illness caused by avian flu ("bird flu").


Becoming infected with influenza (commonly known as "the flu") is much more dangerous to your health than receiving the vaccine to protect against it. Influenza causes thousands of deaths each year, and hundreds of thousands of hospitalizations. Like any medicine, this vaccine can cause side effects, but the risk of serious side effects is extremely low.


What should I discuss with my healthcare provider before receiving this vaccine?


Do not receive this vaccine if you have ever had an allergic reaction to a flu vaccine, or if you have:

  • an active or uncontrolled neurologic disorder (such as Parkinson's disease, Alzheimer's disease, or epilepsy);




  • a history of Guillain-Barré syndrome (especially if you had it within 6 weeks after having a flu vaccine); or




  • if you are allergic to chicken or egg products.



Before receiving influenza virus vaccine, tell your doctor if you are allergic to any drugs, or if you have:



  • a bleeding or blood clotting disorder such as hemophilia or easy bruising;




  • a neurologic disorder or disease affecting the brain (or if this was a reaction to a previous vaccine);




  • an allergy to latex rubber;




  • a weak immune system caused by disease, bone marrow transplant, or by using certain medicines or receiving cancer treatments; or




  • if you are taking a blood thinner such as warfarin (Coumadin).



You can still receive a vaccine if you have a cold or fever. In the case of a more severe illness with a fever or any type of infection, wait until you get better before receiving this vaccine.


Vaccines may be harmful to an unborn baby and generally should not be given to a pregnant woman. However, not vaccinating the mother could be more harmful to the baby if the mother becomes infected with a disease that this vaccine could prevent. Your doctor will decide whether you should receive this vaccine, especially if you have a high risk of infection with influenza. It is not known whether influenza virus vaccine passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. This vaccine should not be given to a child younger than 6 months old.

How is this given?


Some brands of this vaccine are made for use in adults and not in children. Your child's doctor can recommend the best influenza virus vaccine for your child.

This vaccine is given as an injection (shot) into a muscle. You will receive this injection in a doctor's office or other clinic setting.


You should receive a flu vaccine every year. Your immunity will gradually decrease over the 12 months after you receive the influenza virus vaccine. Children receiving this vaccine may need a booster shot one month after receiving the first vaccine.


The influenza virus vaccine is usually given in October or November. Some people may need to have their vaccines earlier or later. Follow your doctor's instructions.


Your doctor may recommend treating fever and pain with an aspirin-free pain reliever such as acetaminophen (Tylenol) or ibuprofen (Motrin, Advil, and others) when the shot is given and for the next 24 hours. Follow the label directions or your doctor's instructions about how much of this medicine to take.


It is especially important to prevent fever from occurring if you have a seizure disorder such as epilepsy.


What happens if I miss a dose?


Since flu shots are usually given only one time per year, you will most likely not be on a dosing schedule. Call your doctor if you forget to receive your yearly flu shot in October or November.


If your child misses a booster dose of this vaccine, call your doctor for instructions.


What happens if I overdose?


An overdose of this vaccine is unlikely to occur.


What should I avoid before or after receiving this vaccine?


Follow your doctor's instructions about any restrictions on food, beverages, or activity after you receive this vaccine.


Influenza virus injectable vaccine side effects


Influenza virus injectable (killed virus) vaccine will not cause you to become ill with the flu virus that it contains. However, you may have flu-like symptoms at any time during flu season that may be caused by other strains of influenza virus.


You should not receive a booster vaccine if you had a life-threatening allergic reaction after the first shot. Keep track of any and all side effects you have after receiving this vaccine. If you ever have to receive another influenza virus vaccine in the future, you will need to tell the doctor if the first shot caused any side effects. Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:

  • severe weakness or unusual feeling in your arms and legs (may occur 2 to 4 weeks after you receive the vaccine);




  • high fever; or




  • unusual bleeding.



Less serious side effects may include:



  • low fever, chills;




  • redness, bruising, pain, swelling, or a lump where the vaccine was injected;




  • headache, tired feeling; or




  • joint or muscle pain.



This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect influenza virus injectable vaccine?


Before receiving this vaccine, tell your doctor if you are using phenytoin (Dilantin), theophylline (Respbid, Slo-Bid, Theodur, Uniphyl), or a blood thinner (warfarin, Coumadin).


Also tell the doctor if you have recently received drugs or treatments that can weaken the immune system, including:



  • an oral, nasal, inhaled, or injectable steroid medicine;




  • medications to treat psoriasis, rheumatoid arthritis, or other autoimmune disorders, such as azathioprine (Imuran), efalizumab (Raptiva), etanercept (Enbrel), leflunomide (Arava), and others; or




  • medicines to treat or prevent organ transplant rejection, such as basiliximab (Simulect), cyclosporine (Sandimmune, Neoral, Gengraf), muromonab-CD3 (Orthoclone), mycophenolate mofetil (CellCept), sirolimus (Rapamune), or tacrolimus (Prograf).



This list is not complete and there may be other drugs that can interact with this vaccine. Tell your doctor about all the prescription and over-the-counter medications you have received. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.



More Fluarix resources


  • Fluarix Side Effects (in more detail)
  • Fluarix Use in Pregnancy & Breastfeeding
  • Fluarix Drug Interactions
  • Fluarix Support Group
  • 0 Reviews for Fluarix - Add your own review/rating


Compare Fluarix with other medications


  • Influenza Prophylaxis


Where can I get more information?


  • Your doctor or pharmacist may have information about influenza virus vaccine written for health professionals that you may read. You may also find additional information from your local health department or the Centers for Disease Control and Prevention.

See also: Fluarix side effects (in more detail)


Lice-X Topical


Generic Name: pyrethrum extract and piperonyl butoxide (Topical route)


pye-REE-thrum EX-trackt, PIP-er-oh-nil byoo-TOX-ide


Commonly used brand name(s)

In the U.S.


  • A200 Maximum Strength

  • A200 Time-Tested Formula

  • Lice-X

  • Licide

  • Medi-Lice Maximum Strength

  • Pronto Maximum Strength

  • Pyrinex

  • Pyrinyl

  • Rid

  • Tisit

Available Dosage Forms:


  • Gel/Jelly

  • Liquid

  • Shampoo

  • Kit

  • Foam

Therapeutic Class: Pediculicide


Chemical Class: Pyrethrums


Uses For Lice-X


Medicine containing pyrethrins is used to treat head, body, and pubic lice infections. This medicine is absorbed by the lice and destroys them by acting on their nervous systems. It does not affect humans in this way. The piperonyl butoxide is included to make the pyrethrins more effective in killing the lice. This combination medicine is known as a pediculicide.


This medicine is available without a prescription.


Before Using Lice-X


In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:


Allergies


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Pediatric


Although there is no specific information comparing use of pyrethrins and piperonyl butoxide combination in children with use in other age groups, this medicine is not expected to cause different side effects or problems in children than it does in adults.


Geriatric


Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults. Although there is no specific information comparing use of pyrethrins and piperonyl butoxide combination medicine in the elderly with use in other age groups, this medicine is not expected to cause different side effects or problems in older people than it does in younger adults.


Pregnancy








Pregnancy CategoryExplanation
All TrimestersCAnimal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.


Interactions with Medicines


Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.


Interactions with Food/Tobacco/Alcohol


Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.


Other Medical Problems


The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:


  • Inflammation of the skin (severe)—Use of pyrethrins and piperonyl butoxide combination may make the condition worse

Proper Use of pyrethrum extract and piperonyl butoxide

This section provides information on the proper use of a number of products that contain pyrethrum extract and piperonyl butoxide. It may not be specific to Lice-X. Please read with care.


Pyrethrins and piperonyl butoxide combination medicine usually comes with patient directions. Read them carefully before using this medicine.


Use this medicine only as directed. Do not use more of it and do not use it more often than recommended on the label. To do so may increase the chance of absorption through the skin and the chance of side effects.


Keep pyrethrins and piperonyl butoxide combination medicine away from the mouth and do not inhale it. This medicine is harmful if swallowed or inhaled.


To lessen the chance of inhaling this medicine, apply it in a well-ventilated room (for example, one with free flowing air or with a fan turned on).


Keep this medicine away from the eyes and other mucous membranes, such as the inside of the nose, mouth, or vagina, because it may cause irritation. If you accidentally get some in your eyes, flush them thoroughly with water at once.


Do not apply this medicine to the eyelashes or eyebrows . If they become infected with lice, check with your doctor.


To use the gel or solution form of this medicine:


  • Apply enough medicine to thoroughly wet the dry hair and scalp or skin. Allow the medicine to remain on the affected areas for exactly 10 minutes.

  • Then, thoroughly wash the affected areas with warm water and soap or regular shampoo. Rinse thoroughly and dry with a clean towel.

To use the shampoo form of this medicine:


  • Apply enough medicine to thoroughly wet the dry hair and scalp or skin. Allow the medicine to remain on the affected areas for exactly 10 minutes.

  • Then use a small amount of water and work shampoo into the hair and scalp or skin until a lather forms. Rinse thoroughly and dry with a clean towel.

After rinsing and drying, use a nit removal comb (special fine-toothed comb, usually included with this medicine) to remove the dead lice and eggs (nits) from hair.


Immediately after using this medicine, wash your hands to remove any medicine that may be on them.


This medicine should be used again in 7 to 10 days after the first treatment in order to kill any newly hatched lice.


Lice can easily move from one person to another by close body contact. This can happen also by direct contact with such things as clothing, hats, scarves, bedding, towels, washcloths, hairbrushes and combs, or the hair of infected persons. Therefore, all members of your household should be examined for lice and receive treatment if they are found to be infected.


To use this medicine for pubic (crab) lice:


  • Your sexual partner may also need to be treated, since the infection may spread to persons in close contact. If your partner is not being treated or if you have any questions about this, check with your doctor.

Dosing


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.


The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.


  • For topical dosage forms (gel, solution shampoo, and topical solution):
    • For head, body, or pubic lice:
      • Adults and children—Use one time, then repeat one time in seven to ten days.



Storage


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.


Keep out of the reach of children.


Do not keep outdated medicine or medicine no longer needed.


Precautions While Using Lice-X


To prevent reinfection or spreading of the infection to other people, good health habits are also required. These include the following:


  • For head lice
    • Machine wash all clothing (including hats, scarves, and coats), bedding, towels, and washcloths in very hot water and dry them by using the hot cycle of a dryer for at least 20 minutes. Clothing or bedding that cannot be washed should be dry-cleaned or sealed in a plastic bag for 2 weeks.

    • Shampoo all wigs and hairpieces.

    • Wash all hairbrushes and combs in very hot soapy water (above 130 °F) for 5 to 10 minutes and do not share them with other people.

    • Clean the house or room by thoroughly vacuuming upholstered furniture, rugs, and floors.


  • For body lice
    • Machine wash all clothing, bedding, towels, and washcloths in very hot water and dry them by using the hot cycle of a dryer for at least 20 minutes. Clothing or bedding that cannot be washed should be dry-cleaned or sealed in a plastic bag for 2 weeks.

    • Clean the house or room by thoroughly vacuuming upholstered furniture, rugs, and floors.


  • For pubic lice
    • Machine wash all clothing (especially underwear), bedding, towels, and washcloths in very hot water and dry them by using the hot cycle of a dryer for at least 20 minutes. Clothing or bedding that cannot be washed should be dry-cleaned or sealed in a plastic bag for 2 weeks.

    • Scrub toilet seats frequently.


Lice-X Side Effects


Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.


Check with your doctor as soon as possible if any of the following side effects occur:


Less common or rare
  • Skin irritation not present before use of this medicine

  • skin rash or infection

  • sneezing (sudden attacks of)

  • stuffy or runny nose

  • wheezing or difficulty in breathing

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.


Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.



The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.


The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.


More Lice-X Topical resources


  • Lice-X Topical Use in Pregnancy & Breastfeeding
  • Lice-X Topical Support Group
  • 0 Reviews for Lice-X Topical - Add your own review/rating


Compare Lice-X Topical with other medications


  • Head Lice
  • Lice

Sunday, 15 April 2012

Cardene SR 30 and 45mg





1. Name Of The Medicinal Product



Cardene SR 30



Cardene SR 45


2. Qualitative And Quantitative Composition



Nicardipine hydrochloride 30 mg



Nicardipine hydrochloride 45 mg



3. Pharmaceutical Form



Sustained release capsules



4. Clinical Particulars



4.1 Therapeutic Indications



Treatment of mild to moderate hypertension.



4.2 Posology And Method Of Administration



Adults



Starting dose: 30 mg every 12 hours titrating upwards as required.



Usual effective dose: 45 mg every 12 hours (range 30 mg to 60 mg every 12 hours).



Individually adjust the dose for each patient. Where appropriate Cardene SR may also be used in combination with beta-blockers and/or diuretics.



Use in the elderly:



Starting dose: 30 mg every 12 hours. Titrate upwards with care as nicardipine may lower systolic pressure more than diastolic pressure in these patients.



Children:



Cardene SR is not recommended for use in patients under the age of 18.



4.3 Contraindications



i) Use in pregnancy and lactation.



ii) Hypersensitivity to nicardipine hydrochloride or other dihydropyridines because of the theoretical risk of cross reactivity.



iii) As part of the effect of nicardipine is secondary to reduced afterload, the drug should not be given to patients with advanced aortic stenosis. Reduction in diastolic pressure in these patients may worsen rather than improve myocardial oxygen balance.



iv) Cardene should not be used in cardiogenic shock, clinically significant aortic stenosis and during or within one month of a myocardial infarction.



v) Cardene should not be used for secondary prevention of myocardial infarction.



4.4 Special Warnings And Precautions For Use



If used in combination with diuretics or beta-blockers, careful titration of Cardene SR is advised to avoid excessive reduction in blood pressure.



If switching from beta-blockers to Cardene SR, gradually reduce the beta-blocker dose (preferably over 8 – 10 days) since nicardipine gives no protection against the dangers of abrupt beta-blocker withdrawal.



Stop Cardene SR in patients experiencing ischaemic pain within 30 minutes of starting therapy or after increasing the dose.



Use in patients with congestive heart failure or poor cardiac reserve:



Haemodynamic studies in patients with heart failure have shown that nicardipine reduces afterload and improves overall haemodynamics. In one study, intravenous nicardipine reduced myocardial contractility in patients with severe heart failure despite increases in cardiac index and ejection fraction noted in the same patients.



Since nicardipine has not been extensively studied in patients with severe left ventricular dysfunction and cardiac failure, one must consider that worsening of cardiac failure may occur.



Use in patients with impaired hepatic or renal function:



Since Cardene is subject to first-pass metabolism, use with caution in patients with impaired liver function or reduced hepatic blood flow. Patients with severe liver disease showed elevated blood levels and the half-life of nicardipine was prolonged. Cardene blood levels may also be elevated in some renally impaired patients. Therefore the lowest starting dose and extending the dosing interval should be individually considered in these patients.



Use in patients following a stroke (infarction or haemorrhage):



Avoid inducing systemic hypotension when administering Cardene SR to these patients.



Laboratory tests:



Transient elevations of alkaline phosphatase, serum bilirubin, SGPT, SGOT and glucose, have been observed. BUN and creatinine may also become elevated. While out-of-range values were seen in T3, T4 and TSH, the lack of consistent alterations suggest that any changes were not drug-related.



Treatment with short acting nicardipine may induce an exaggerated fall in blood pressure and reflex tachycardia which can cause cardiovascular complications such as myocardial and cerebrovascular ischaemia.



There has been some concern about increased mortality and morbidity in the treatment of ischaemic heart disease using higher than recommended doses of some other short-acting dihydropyridines.



Patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicine.



4.5 Interaction With Other Medicinal Products And Other Forms Of Interaction



Digoxin



Careful monitoring of serum digoxin levels is advised in patients also receiving Cardene as levels may be increased.



Propranolol, Dipyridamole, Warfarin, Quinidine, Naproxen:



Therapeutic concentrations of these drugs does not change the in vitro plasma protein binding of nicardipine.



Cimetidine:



Cimetidine increases nicardipine plasma levels. Carefully monitor patients receiving both drugs.



Fentanyl Anaesthesia:



Severe hypotension has been reported during fentanyl anaesthesia with concomitant use of a beta-blocker and calcium blockade. Even though such interactions have not been seen in clinical trials, such hypotensive episodes should be vigorously treated with conventional therapy such as intravenous fluids.



Ciclosporin:



Monitor ciclosporin plasma levels and reduce dosage accordingly in patients concomitantly receiving nicardipine as elevated ciclosporin levels have been reported.



Rifampicin:



Rifampicin can interact with other dihydropyridines to substantially reduce their plasma levels and so rifampicin and nicardipine should be used together with caution.



As with other dihydropyridines, nicardipine should not be taken with grapefruit juice because bioavailability may be increased.



Cardene may be used in combination with beta-blocking and other anti-hypertensive drugs but the possibility of an additive effect resulting in postural hypotension should be considered.



4.6 Pregnancy And Lactation



See contra-indications.



4.7 Effects On Ability To Drive And Use Machines



None known.



4.8 Undesirable Effects



Most are expected consequences of the vasodilator effects of Cardene SR.



The most frequent side-effects reported are headache, pedal oedema, heat sensation and/or flushing, palpitations, nausea and dizziness.



Other side-effects noted in clinical trials include the following:



Cardiovascular System: As with the use of other sustained release dihydropyridines in patients with ischaemic heart disease, exacerbation of angina pectoris may occur rarely at the start of treatment with Cardene SR. The occurrence of myocardial infarction has been reported although it is not possible to distinguish such an event from the natural course of ischaemic heart disease.



Central Nervous System: Drowsiness, insomnia, tinnitus, paraesthesia, functional disorders.



Skin: Itching, rashes.



Hepato-Renal: Impairment, frequency.



Dyspnoea, gastro-intestinal upset and, rarely, depression, impotence and thrombocytopenia, have also been reported.



4.9 Overdose



Symptoms may include marked hypotension, bradycardia, palpitations, flushing, drowsiness, confusion and slurred speech. In laboratory animals, overdosage also resulted in reversible hepatic function abnormalities, sporadic focal hepatic necrosis and progressive atrioventricular conduction block.



Use routine measures (eg gastric lavage) including monitoring of cardiac and respiratory functions. Position the patient to avoid cerebral anoxia. Frequent blood pressure determinations are essential. Vasopressors are clinically indicated for patients exhibiting the effects of calcium entry blockade.



5. Pharmacological Properties



5.1 Pharmacodynamic Properties



Mode of action



Cardene is a potent calcium channel blocker. Pharmacological studies suggest it is highly selective for the peripheral vasculature over the myocardium accounting for its minimal negative inotropic effects and marked peripheral vasodilatation when used clinically.



In mild to moderate hypertensive patients Cardene SR has been shown to reduce blood pressure and maintain control over 24 hours, only if the doses are regularly administered exactly 12 hours apart.



Electrophysiologic effects:



Electrophysiological studies in man show that Cardene does not depress sinus node function or atrial or ventricular conduction in patients with either normal or decreased electrical conduction systems. Refractory periods of the His-Purkinje system were actually shortened slightly by nicardipine and SA conduction time was improved.



5.2 Pharmacokinetic Properties



Cardene Capsules are completely absorbed with plasma levels detectable 20 minutes following an oral dose. Maximal plasma levels are generally achieved between one and four hours. Cardene SR is subject to saturable first pass metabolism with somewhat lower bioavailability than the standard capsule formulation of nicardipine (about 35% following a 30mg oral standard capsule at steady state) except at the 60mg dose. Minimum plasma levels produced by equivalent daily doses are similar. Cardene SR thus exhibits significantly reduced fluctuation in plasma levels in comparison to standard nicardipine capsules.



When Cardene SR is taken with a high fat meal, fluctuation in plasma levels are reduced.



Cardene is extensively metabolised by the liver; none of the metabolites possess significant biological activity.



5.3 Preclinical Safety Data



Please refer to section 4.6 Pregnancy and Lactation.



6. Pharmaceutical Particulars



6.1 List Of Excipients



Starch, Pregelatinised



Magnesium Stearate



Microcrystalline cellulose



Maize Starch



Lactose



Methacrylic acid co-polymer



Cardene SR 30mg



Capsule shell body



Titanium Dioxide E171



Gelatin



Cardene SR 45mg



Capsule shell body



Titanium Dioxide E171



Gelatin



Indigotine E132



Cardene SR 30mg



Capsule shell cap



Titanium Dioxide E171



Gelatin



Cardene SR 45mg



Capsule shell cap



Titanium Dioxide E171



Gelatin



Indigotine E132



Cardene SR 30mg and Cardene SR 45mg



Printing ink: Opacode Red S-1-25082



Shellac



Iron oxide, red (E172)



n-Butyl alcohol NF



Propylene glycol (E1520)



Purified water



Ammonia solution



Industrial methylated spirit



Isopropyl alcohol



Printing Ink: TekPrint SW-1102 Red Ink



Shellac



Dehydrated alcohol



Isopropyl alcohol



Butyl alcohol



Propylene glycol



Strong ammonia solution



Iron oxide, red (E172)



Potassium hydroxide



Purified water



6.2 Incompatibilities



None known.



6.3 Shelf Life



60 months.



6.4 Special Precautions For Storage



Protect from light and excessive humidity. Do not store above 25°C.



6.5 Nature And Contents Of Container



Blister packs of 56



Blister packs of 14



Securitainers of 100



6.6 Special Precautions For Disposal And Other Handling



No special instructions required.



ADMINISTRATIVE DATA


7. Marketing Authorisation Holder



Astellas Pharma Limited



Lovett House



Lovett Road



Staines



TW18 3AZ



United Kingdom



8. Marketing Authorisation Number(S)



Cardene SR 30mg - PL 00166/0183



Cardene SR 45mg - PL 00166/0184



9. Date Of First Authorisation/Renewal Of The Authorisation



1 July 1998/ 15 July 2002



10. Date Of Revision Of The Text



8th March 2010



11. LEGAL CATEGORY


POM




Friday, 13 April 2012

Glycopyrrolate Solution


Pronunciation: GLYE-koe-PIR-oh-late
Generic Name: Glycopyrrolate
Brand Name: Cuvposa


Glycopyrrolate Solution is used for:

Reducing chronic, severe drooling caused by certain conditions (eg, cerebral palsy) in patients 3 to 16 years old. It may also be used for other conditions as determined by your doctor.


Glycopyrrolate Solution is an anticholinergic. It works by blocking the activity of the glands that produce saliva.


Do NOT use Glycopyrrolate Solution if:


  • you are allergic to any ingredient in Glycopyrrolate Solution

  • you have glaucoma, trouble urinating, certain stomach or bowel problems (eg, blockage, bowel muscle problems, severe ulcerative colitis, toxic megacolon), myasthenia gravis, or heart problems caused by bleeding

  • you are taking a solid oral doseform of potassium (eg, tablet)

Contact your doctor or health care provider right away if any of these apply to you.



Before using Glycopyrrolate Solution:


Some medical conditions may interact with Glycopyrrolate Solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have nerve problems (eg, autonomic neuropathy), liver or kidney problems, thyroid problems, eye problems (eg, increased pressure in the eye), or a family history of glaucoma

  • if you have heart problems (eg, coronary heart disease, heart failure), fast or irregular heartbeat, or high blood pressure

  • if you have stomach or bowel problems (eg, ulcerative colitis), a hiatal hernia caused by reflux disease, or if you have an ileostomy or colostomy

  • if you have a history of constipation problems

Some MEDICINES MAY INTERACT with Glycopyrrolate Solution. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Amantadine because it may increase the risk of Glycopyrrolate Solution's side effects

  • Atenolol, digoxin, or metformin because the risk of their side effects may be increased by Glycopyrrolate Solution

  • Haloperidol or levodopa because their effectiveness may be decreased by Glycopyrrolate Solution

This may not be a complete list of all interactions that may occur. Ask your health care provider if Glycopyrrolate Solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Glycopyrrolate Solution:


Use Glycopyrrolate Solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • An extra patient leaflet is available with Glycopyrrolate Solution. Talk to your pharmacist if you have questions about this information.

  • Take Glycopyrrolate Solution by mouth on an empty stomach at least 1 hour before or 2 hours after eating.

  • Use a measuring cup and oral syringe marked for medicine dosing. Use the measuring cup to measure the correct dose, then use the oral syringe to transfer the medicine from the cup to the mouth. Ask your pharmacist for help if you are unsure of how to measure your dose.

  • Take Glycopyrrolate Solution on a regular schedule to get the most benefit from it.

  • Continue to take Glycopyrrolate Solution even if your condition improves. Do not miss any doses.

  • If you miss a dose of Glycopyrrolate Solution, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Glycopyrrolate Solution.



Important safety information:


  • Glycopyrrolate Solution may cause drowsiness or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Glycopyrrolate Solution with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

  • Do NOT take more than the recommended dose without checking with your doctor.

  • Do not become overheated in hot weather or while you are being active; heatstroke may occur.

  • If constipation occurs, contact your doctor for instructions.

  • Glycopyrrolate Solution should be used with extreme caution in CHILDREN younger than 3 years old; safety and effectiveness in these children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: It is not known if Glycopyrrolate Solution can cause harm to the fetus. If you become pregnant, contact your doctor. Your will need to discuss the benefits and risks of using Glycopyrrolate Solution while you are pregnant. It is not known if Glycopyrrolate Solution is found in breast milk. If you are or will be breast-feeding while you use Glycopyrrolate Solution, check with your doctor. Discuss any possible risks to your baby.


Possible side effects of Glycopyrrolate Solution:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Blurred vision; constipation; drowsiness; dry mouth; flushing; headache; nasal congestion; upper respiratory infection; vomiting.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); diarrhea; frequent or painful urination; mental or mood changes (eg, irritability, crying); seizures; severe or persistent nausea or vomiting; stomach pain or bloating; symptoms of dehydration (eg, very dry mouth, skin, or eyes; fast or irregular heartbeat); symptoms of heatstroke (eg, fever; hot, red skin; decreased alertness; fast, weak pulse; fast, shallow breathing); trouble urinating.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Glycopyrrolate side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include coma; fever; muscle pain; seizures; stomach pain or bloating; uncontrolled muscle movements.


Proper storage of Glycopyrrolate Solution:

Store Glycopyrrolate Solution at room temperature between 68 and 77 degrees F (20 and 25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Glycopyrrolate Solution out of the reach of children and away from pets.


General information:


  • If you have any questions about Glycopyrrolate Solution, please talk with your doctor, pharmacist, or other health care provider.

  • Glycopyrrolate Solution is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Glycopyrrolate Solution. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Glycopyrrolate resources


  • Glycopyrrolate Side Effects (in more detail)
  • Glycopyrrolate Use in Pregnancy & Breastfeeding
  • Drug Images
  • Glycopyrrolate Drug Interactions
  • Glycopyrrolate Support Group
  • 0 Reviews for Glycopyrrolate - Add your own review/rating


Compare Glycopyrrolate with other medications


  • Anesthesia
  • Excessive Salivation
  • Peptic Ulcer

Wednesday, 11 April 2012

Ultrase MT Capsules (Enteric-Coated)


Pronunciation: PAN-kree-LYE-pase
Generic Name: Pancrelipase
Brand Name: Examples include Pancrecarb MS and Ultrase MT


Ultrase MT Capsules (Enteric-Coated) is used for:

Improving food digestion in patients who cannot digest food properly because they have a pancreas problem (exocrine pancreatic insufficiency) caused by cystic fibrosis or certain other conditions.


Ultrase MT Capsules (Enteric-Coated) is a digestive enzyme combination. It works by helping the body to digest protein, starch, and fat.


Do NOT use Ultrase MT Capsules (Enteric-Coated) if:


  • you are allergic to any ingredient in Ultrase MT Capsules (Enteric-Coated) or to pork

  • you have inflammation of the pancreas (acute pancreatitis) or a flare-up of long-term pancreas problems

Contact your doctor or health care provider right away if any of these apply to you.



Before using Ultrase MT Capsules (Enteric-Coated):


Some medical conditions may interact with Ultrase MT Capsules (Enteric-Coated). Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have gout, high uric acid levels, or a history of kidney problems

  • if you have a history of pancreas problems, stomach or bowel problems (eg, blockage, inflammation, short bowel syndrome, Crohn disease), or intestinal surgery

  • if you have trouble swallowing capsules

Some MEDICINES MAY INTERACT with Ultrase MT Capsules (Enteric-Coated). However, no specific interactions with Ultrase MT Capsules (Enteric-Coated) are known at this time.


Ask your health care provider if Ultrase MT Capsules (Enteric-Coated) may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Ultrase MT Capsules (Enteric-Coated):


Use Ultrase MT Capsules (Enteric-Coated) as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Take Ultrase MT Capsules (Enteric-Coated) by mouth with each meal or snack as directed by your doctor.

  • Swallow Ultrase MT Capsules (Enteric-Coated) whole. Do not crush, chew, or hold Ultrase MT Capsules (Enteric-Coated) in your mouth before swallowing. Doing so may increase the risk of mouth irritation from Ultrase MT Capsules (Enteric-Coated).

  • Drink a glass of water or juice immediately after you take Ultrase MT Capsules (Enteric-Coated).

  • If you cannot swallow Ultrase MT Capsules (Enteric-Coated) whole, open it and sprinkle the contents over a small amount of acidic soft food (eg, applesauce, gelatin) that does not need to be chewed. Do not crush or chew the contents of the capsule. Mix the medicine with the food and swallow the entire mixture right away. Follow with a glass of water or juice. Be sure that none of the medicine is left in your mouth. Check with your doctor if you are unsure which foods you may mix with Ultrase MT Capsules (Enteric-Coated).

  • Drinking extra fluids while you are taking Ultrase MT Capsules (Enteric-Coated) is recommended. Check with your doctor for instructions.

  • If you miss a dose of Ultrase MT Capsules (Enteric-Coated), skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once or take a dose without a snack or a meal.

Ask your health care provider any questions you may have about how to use Ultrase MT Capsules (Enteric-Coated).



Important safety information:


  • Do NOT take more than the recommended dose without checking with your doctor.

  • Do not switch between brands of Ultrase MT Capsules (Enteric-Coated) without checking with your doctor.

  • Ultrase MT Capsules (Enteric-Coated) may increase the risk of developing a rare, serious condition called fibrosing colonopathy. When this occurs, it is usually with high doses over a long period of time. It has been most commonly reported in children with cystic fibrosis. Contact your doctor right away if you experience unusual or severe nausea, vomiting, or stomach pain, or severe or persistent loose stools, constipation, or diarrhea.

  • Ultrase MT Capsules (Enteric-Coated) comes from pork (pig) pancreas tissue. There is an extremely rare risk of developing a viral disease from this product. No cases of viral disease from pork pancreas products have been identified.

  • Caution is advised when using Ultrase MT Capsules (Enteric-Coated) in CHILDREN; they may be more sensitive to its effects, especially fibrosing colonopathy.

  • PREGNANCY and BREAST-FEEDING: It is not known if Ultrase MT Capsules (Enteric-Coated) can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Ultrase MT Capsules (Enteric-Coated) while you are pregnant. It is not known if Ultrase MT Capsules (Enteric-Coated) is found in breast milk. If you are or will be breast-feeding while you use Ultrase MT Capsules (Enteric-Coated), check with your doctor. Discuss any possible risks to your baby.


Possible side effects of Ultrase MT Capsules (Enteric-Coated):


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Bloating; constipation; diarrhea; gas; headache; nausea; stomach pain; vomiting.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); painful, swollen joints; severe or persistent loose stools, diarrhea, or constipation; severe or unusual nausea, vomiting, or stomach pain.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Ultrase MT (Enteric-Coated) side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.


Proper storage of Ultrase MT Capsules (Enteric-Coated):

Store Ultrase MT Capsules (Enteric-Coated) at room temperature, between 59 and 77 degrees F (15 and 25 degrees C). Store in the original container, away from heat, moisture, and light. Do not refrigerate. Do not store in the bathroom. Keep Ultrase MT Capsules (Enteric-Coated) out of the reach of children and away from pets.


General information:


  • If you have any questions about Ultrase MT Capsules (Enteric-Coated), please talk with your doctor, pharmacist, or other health care provider.

  • Ultrase MT Capsules (Enteric-Coated) is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Ultrase MT Capsules (Enteric-Coated). If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Ultrase MT Capsules (Enteric-Coated) resources


  • Ultrase MT Capsules (Enteric-Coated) Side Effects (in more detail)
  • Ultrase MT Capsules (Enteric-Coated) Use in Pregnancy & Breastfeeding
  • Drug Images
  • Ultrase MT Capsules (Enteric-Coated) Drug Interactions
  • Ultrase MT Capsules (Enteric-Coated) Support Group
  • 10 Reviews for Ultrase MT (Enteric-Coated) - Add your own review/rating


Compare Ultrase MT Capsules (Enteric-Coated) with other medications


  • Chronic Pancreatitis
  • Cystic Fibrosis
  • Pancreatic Exocrine Dysfunction

Tuesday, 10 April 2012

High Risk Percutaneous Transluminal Angioplasty Medications


Drugs associated with High Risk Percutaneous Transluminal Angioplasty

The following drugs and medications are in some way related to, or used in the treatment of High Risk Percutaneous Transluminal Angioplasty. This service should be used as a supplement to, and NOT a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners.





Drug List:

Monday, 9 April 2012

Solfoton


Generic Name: phenobarbital (FEE noe BAR bi tal)

Brand Names: Solfoton


What is Solfoton (phenobarbital)?

Phenobarbital is in a group of drugs called barbiturates (bar-BIT-chur-ates). Phenobarbital slows the activity of your brain and nervous system.


Phenobarbital is used to treat or prevent seizures. It is also used short-term to treat insomnia, or as a sedative before surgery.


Phenobarbital may also be used for purposes not listed in this medication guide.


What is the most important information I should know about Solfoton (phenobarbital)?


Do not use phenobarbital if you are pregnant. It could harm the unborn baby. Phenobarbital may also cause addiction or withdrawal symptoms in a newborn if the mother takes the medication during pregnancy. Phenobarbital can make birth control pills less effective. Ask your doctor about using a non-hormone method of birth control (such as a condom, diaphragm, spermicide) to prevent pregnancy while taking phenobarbital. Phenobarbital may cause a severe allergic reaction. Stop taking phenobarbital and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Do not stop using phenobarbital without first talking to your doctor, even if you feel better. You may have increased seizures if you stop using phenobarbital suddenly. You will need to use less and less before you stop the medication completely.

Some people using this medicine have engaged in activity such as driving, eating, or making phone calls and later having no memory of the activity. If this happens to you, stop taking phenobarbital and talk with your doctor about another treatment for your sleep disorder.


Phenobarbital may be habit-forming and should be used only by the person it was prescribed for. Keep the medication in a secure place where others cannot get to it.

What should I discuss with my healthcare provider before taking Solfoton (phenobarbital)?


Some people using this medicine have engaged in activity such as driving, eating, or making phone calls and later having no memory of the activity. If this happens to you, stop taking phenobarbital and talk with your doctor about another treatment for your sleep disorder.


You should not take this medication if you are allergic to phenobarbital or other barbiturates (Nembutal, Seconal, and others), or if you have:

  • porphyria;



  • severe liver disease;


  • a history of addiction to a barbiturate, sedative (Valium, Xanax, and others); or




  • severe asthma, chronic obstructive pulmonary disorder (COPD), or other breathing disorder.



To make sure you can safely take phenobarbital, tell your doctor if you have any of these other conditions:



  • temporary or chronic pain;



  • liver disease;

  • kidney disease;


  • pheochromocytoma (tumor of the adrenal gland);




  • a pituitary gland disorder;




  • a history of depression, mental illness, or suicide attempt; or




  • a history of drug or alcohol addiction.




Phenobarbital may be habit forming and should be used only by the person it was prescribed for. Never share phenobarbital with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it. FDA pregnancy category D. Do not use phenobarbital if you are pregnant. It could harm the unborn baby. Phenobarbital may also cause addiction or withdrawal symptoms in a newborn if the mother takes the medication during pregnancy. Use effective birth control, and tell your doctor if you become pregnant during treatment. Phenobarbital can make birth control pills less effective. Ask your doctor about using a non-hormone method of birth control (such as a condom, diaphragm, spermicide) to prevent pregnancy while taking phenobarbital. Phenobarbital can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take Solfoton (phenobarbital)?


Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.


Take this medicine with a full glass of water.

If you are taking this medicine to treat insomnia, take it only at bedtime. Do not use phenobarbital for longer than 2 weeks to treat insomnia, unless your doctor has told you to.


Take phenobarbital only when you are getting ready for several hours of sleep. You may fall asleep very quickly after taking the medicine.

Do not change your dose of phenobarbital without your doctor's advice. Tell your doctor if the medication does not seem to work as well in treating your condition.


If you are taking phenobarbital to treat seizures, keep taking the medication even if you feel fine. You may have increased seizures or withdrawal symptoms if you stop using phenobarbital suddenly. You will need to use less and less before you stop the medication completely.

If you use this medication long-term, your blood will need to be tested often. Visit your doctor regularly.


Store at room temperature away from moisture and heat.

Keep track of the amount of medicine used from each new bottle. Phenobarbital is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.


What happens if I miss a dose?


Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of phenobarbital can be fatal.

Overdose symptoms may include slow or shallow breathing, blurred vision, extreme drowsiness, urinating less than usual or not at all, feeling light-headed, or fainting.


What should I avoid while taking Solfoton (phenobarbital)?


This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Drinking alcohol can increase some of the side effects of phenobarbital.

Solfoton (phenobarbital) side effects


Phenobarbital may cause a severe allergic reaction. Stop taking phenobarbital and get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:

  • restless muscle movements in your eyes, tongue, jaw, or neck;




  • slow heartbeat, shallow breathing;




  • feeling light-headed, fainting;




  • a fever or a sore throat;




  • sores in your mouth;




  • easy bruising or bleeding; or




  • broken blood vessels under your skin.



Less serious side effects may include:



  • drowsiness or dizziness;




  • problems with memory or concentration;




  • excitement, irritability, aggression, or confusion (especially in children or older adults);




  • loss of balance or coordination;




  • nausea, constipation;




  • headache; or




  • "hangover" effect (drowsiness the day after a dose).



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect Solfoton (phenobarbital)?


Before using phenobarbital, tell your doctor if you regularly use other medicines that make you sleepy (such as other sleeping pills or seizure medicines, cold or allergy medicine, narcotic pain medicine, muscle relaxers, and medicine for depression or anxiety). They can add to sleepiness caused by phenobarbital.

Tell your doctor about all other medicines you use, especially:



  • a blood thinner such as warfarin (Coumadin, Jantoven);




  • doxycycline (Doryx, Oracea, Periostat, Vibramycin);




  • other seizure medications such as divalproex (Depakote), phenytoin (Dilantin), or valproic acid (Depakene);




  • an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate);




  • griseofulvin (Grisactin, Fulvicin PG, Grifulvin V);




  • birth control pills or estrogen hormone replacement, including estrogen (Premarin), estradiol (Estrace, Femtrace, and others), progesterone (Progest, Prometrium), and others; or




  • steroids such as prednisone, dexamethasone (Decadron, Hexadrol) fluticasone (Flonase, Advair), methylprednisolone (Medrol), mometasone (Asmanex, Nasonex), and others.



This list is not complete and other drugs may interact with phenobarbital. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.



More Solfoton resources


  • Solfoton Side Effects (in more detail)
  • Solfoton Use in Pregnancy & Breastfeeding
  • Solfoton Drug Interactions
  • Solfoton Support Group
  • 0 Reviews for Solfoton - Add your own review/rating


  • Luminal MedFacts Consumer Leaflet (Wolters Kluwer)

  • Luminal Monograph (AHFS DI)

  • Phenobarbital Prescribing Information (FDA)

  • Phenobarbital Professional Patient Advice (Wolters Kluwer)



Compare Solfoton with other medications


  • Hyperbilirubinemia
  • Insomnia
  • Sedation
  • Seizures


Where can I get more information?


  • Your pharmacist can provide more information about phenobarbital.

See also: Solfoton side effects (in more detail)


Cepacol Dual Relief Sore Throat Mint


Generic Name: benzocaine topical (BENZ oh kane TOP ik al)

Brand Names: Americaine, Americaine Hemorrhoidal, Anacaine, Anbesol Gel, Anbesol Liquid, Babee Teething Lotion, Benzo-O-Stetic, Boil Ease Pain Relieving, Cepacol Extra Strength, Cepacol Fizzlers, Dent-O-Kain, Dermoplast, Detane, Hurricaine, Lanacane, Maintain, Medicone Maximum Strength, Num-Zit, Numzident, Orabase, Orabase Gel-B, Orajel, Orajel Denture, Oral Pain Relief, OraMagic Plus, Outgro Pain Relief, Retre-Gel, Rid-A-Pain, Skeeter Stik, Solarcaine Aerosol, Sting-Kill, Topex, Trocaine, Vagisil Feminine Cream, zilactin-B


What is Cepacol Dual Relief Sore Throat Mint (benzocaine topical)?

Benzocaine is a local anesthetic (numbing medication). It works by blocking nerve signals in your body.


Benzocaine topical is used to reduce pain or discomfort caused by minor skin irritations, sore throat, sunburn, teething pain, vaginal or rectal irritation, ingrown toenails, hemorrhoids, and many other sources of minor pain on a surface of the body. Benzocaine is also used to numb the skin or surfaces inside the mouth, nose, throat, vagina, or rectum to lessen the pain of inserting a medical instrument such as a tube or speculum.


There are many brands and forms of benzocaine topical available and not all brands are listed on this leaflet.


Benzocaine topical may also be used for purposes not listed in this medication guide.


What is the most important information I should know about Cepacol Dual Relief Sore Throat Mint (benzocaine topical)?


There are many brands and forms of benzocaine topical available and not all brands are listed on this leaflet.


Benzocaine topical used in the mouth or throat may cause a life-threatening condition in which the amount of oxygen in your blood stream becomes dangerously low. This condition is called methemoglobinemia (met-HEEM-oh glo-bin-EE-mee-a) and it may occur after only one use of benzocaine or after several uses.

Signs and symptoms of methemoglobinemia may occur within minutes or up to 2 hours after using benzocaine topical in the mouth or throat. GET EMERGENCY MEDICAL HELP IF YOU HAVE ANY OF THESE SYMPTOMS: headache, tired feeling, confusion, fast heart rate, and feeling light-headed or short of breath, with a pale, blue, or gray appearance of your skin, lips, or fingernails.


Do not use benzocaine topical if you have ever had methemoglobinemia in the past. Do not use this medicine on a child younger than 2 years old without medical advice. An overdose of numbing medications can cause fatal side effects if too much of the medicine is absorbed through your skin and into your blood. This is more likely to occur when using a numbing medicine without the advice of a medical doctor (such as during a cosmetic procedure like laser hair removal). Overdose symptoms may include uneven heartbeats, seizure (convulsions), coma, slowed breathing, or respiratory failure (breathing stops).

Use the smallest amount of this medication needed to numb the skin or relieve pain. Do not use large amounts of benzocaine topical, or cover treated skin areas with a bandage or plastic wrap without medical advice. Be aware that many cosmetic procedures are performed without a medical doctor present.


Your body may absorb more of this medication if you use too much, if you apply it over large skin areas, or if you apply heat, bandages, or plastic wrap to treated skin areas. Skin that is cut or irritated may also absorb more topical medication than healthy skin.

Before using benzocaine topical, tell your doctor if you have any type of inherited enzyme deficiency, heart disease, a breathing disorder such as asthma, bronchitis, or emphysema, or if you smoke.


If you are treating a sore throat, call your doctor if the pain is severe or lasts longer than 2 days, especially if you also develop a fever, headache, skin rash, swelling, nausea, vomiting, cough, or breathing problems.


What should I discuss with my health care provider before using Cepacol Dual Relief Sore Throat Mint (benzocaine topical)?


Do not use benzocaine topical if you have ever had methemoglobinemia in the past. An overdose of numbing medications can cause fatal side effects if too much of the medicine is absorbed through your skin and into your blood. This is more likely to occur when using a numbing medicine without the advice of a medical doctor (such as during a cosmetic procedure like laser hair removal). Overdose symptoms may include uneven heartbeats, seizure (convulsions), coma, slowed breathing, or respiratory failure (breathing stops).

Ask a doctor or pharmacist if it is safe for you to take this medicine if you have:



  • asthma, bronchitis, emphysema, or other breathing disorder;




  • heart disease;




  • a personal or family history of methemoglobinemia, or any genetic (inherited) enzyme deficiency; or




  • if you smoke.




FDA pregnancy category C. It is not known whether benzocaine topical will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.. It is not known whether benzocaine topical passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not use this medicine on a child younger than 2 years old without medical advice.

How should I use Cepacol Dual Relief Sore Throat Mint (benzocaine topical)?


Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.


Your body may absorb more of this medication if you use too much, if you apply it over large skin areas, or if you apply heat, bandages, or plastic wrap to treated skin areas. Skin that is cut or irritated may also absorb more topical medication than healthy skin.

Use the smallest amount of medicine needed to numb the skin or relieve pain. Do not use large amounts of benzocaine topical, or cover treated skin areas with a bandage or plastic wrap without medical advice. Be aware that many cosmetic procedures are performed without a medical doctor present.


This medication comes with instructions for safe and effective application. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.


To treat minor skin conditions, apply a thin layer of benzocaine topical to the affected area up to 4 times per day. If using the spray, hold the container 6 to 12 inches away from the skin. Do not spray this medication onto your face. Spray it instead on your hands and then rub it onto the face, avoiding contact with your eyes.


To treat hemorrhoids, clean the area with soap and water before applying benzocaine topical. Apply the medication up to 6 times per day. If you are using the rectal suppository, try to empty your bowel and bladder before inserting the suppository. Remove the outer wrapper from the suppository before inserting it. Avoid handling the suppository too long or it will melt in your hands.


Do not use benzocaine topical to treat large skin areas or deep puncture wounds. Avoid using the medicine on skin that is raw or blistered, such as a severe burn or abrasion.

Call your doctor if your symptoms do not improve or if they get worse within the first 7 days of using benzocaine topical. Also call your doctor if your symptoms had cleared up but then came back.


If you are treating a sore throat, call your doctor if the pain is severe or lasts longer than 2 days, especially if you also develop a fever, headache, skin rash, swelling, nausea, vomiting, cough, or breathing problems.


Store at room temperature away from moisture and heat. Do not freeze.

What happens if I miss a dose?


Since benzocaine topical is used as needed, you may not be on a dosing schedule. If you are using the medication regularly, use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of benzocaine topical applied to the skin can cause life-threatening side effects such as uneven heartbeats, seizure (convulsions), coma, slowed breathing, or respiratory failure (breathing stops).

What should I avoid while taking Cepacol Dual Relief Sore Throat Mint (benzocaine topical)?


Avoid eating within 1 hour after using benzocaine topical on your gums or inside your mouth.


Benzocaine topical is for use only on the surface of your body, or just inside the mouth, vagina, or rectum. Avoid getting this medication in your eyes. Avoid swallowing the gel, liquid, or ointment while applying it to your gums or the inside of your mouth. The throat spray or oral lozenge may be swallowed gradually during use.

Do not apply other medications to the same affected areas you treat with benzocaine topical, unless your doctor has told you otherwise.


Cepacol Dual Relief Sore Throat Mint (benzocaine topical) side effects


Benzocaine topical used in the mouth or throat may cause a life-threatening condition in which the amount of oxygen in your blood stream becomes dangerously low. This condition is called methemoglobinemia (met-HEEM-oh glo-bin-EE-mee-a) and it may occur after only one use of benzocaine or after several uses.

Signs and symptoms may occur within minutes or up to 2 hours after using benzocaine topical in the mouth or throat. GET EMERGENCY MEDICAL HELP IF YOU HAVE:



  • headache, tired feeling, confusion;




  • fast heart rate;




  • feeling light-headed or short of breath; and




  • pale, blue, or gray appearance of your skin, lips, or fingernails.




Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using benzocaine topical and call your doctor at once if you have any of these other serious side effects:

  • headache, weakness, dizziness, breathing problems, fast heart rate, and gray or bluish colored skin (rare but serious side effects of benzocaine);




  • severe burning, stinging, or sensitivity where the medicine is applied;




  • swelling, warmth, or redness; or




  • oozing, blistering, or any signs of infection.



Less serious side effects may include:



  • mild stinging, burning, or itching where the medicine is applied;




  • skin tenderness or redness; or




  • dry white flakes where the medicine was applied.



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect Cepacol Dual Relief Sore Throat Mint (benzocaine topical)?


It is not likely that other drugs you take orally or inject will have an effect on topically applied benzocaine topical. But many drugs can interact with each other. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.



More Cepacol Dual Relief Sore Throat Mint resources


  • Cepacol Dual Relief Sore Throat Mint Side Effects (in more detail)
  • Cepacol Dual Relief Sore Throat Mint Use in Pregnancy & Breastfeeding
  • 0 Reviews for Cepacol Dual Relief Sore Throat Mint - Add your own review/rating


  • Americaine Ointment MedFacts Consumer Leaflet (Wolters Kluwer)

  • Anacaine Advanced Consumer (Micromedex) - Includes Dosage Information

  • Anbesol Extra Strength Advanced Consumer (Micromedex) - Includes Dosage Information

  • Benz-O-Sthetic Gel MedFacts Consumer Leaflet (Wolters Kluwer)

  • Lanacane Aerosol Spray MedFacts Consumer Leaflet (Wolters Kluwer)

  • OraMagic Plus Suspension MedFacts Consumer Leaflet (Wolters Kluwer)

  • Rid-A-Pain Topical Advanced Consumer (Micromedex) - Includes Dosage Information



Compare Cepacol Dual Relief Sore Throat Mint with other medications


  • Oral and Dental Conditions
  • Tonsillitis/Pharyngitis


Where can I get more information?


  • Your pharmacist can provide more information about benzocaine topical.

See also: Cepacol Dual Relief Sore Throat Mint side effects (in more detail)